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Transfer of Montelukast into Human Milk During Lactation.

Submitted by krewersf on 20 November 2018

Montelukast is a commonly used drug in allergies,  and as you know, eveyone has allergies.  This data shows that levels in milk are really quite low (RID = 0.68)  and there is no obvious risk to a breastfeeding infant.  TWH

 

Title: Transfer of Montelukast into Human Milk During Lactation.

Authors: Datta P, Rewers-Felkins K, Baker T, Hale TW.

Transfer of natalizumab into breast milk in a mother with multiple sclerosis.

Submitted by krewersf on 20 November 2018

Natalizumab is a monoclonal antibody that is only used in humans with multiple sclerosis.  It is somewhat toxic, and we were interested to see if this large monoclonal antibody transfers into human milk.  Levels in milk appear low,  but I made a mistake in the timing of the study, and should have drawn milk levels several months longer.  I need to redo this study and go out to about 120 days.   However, at this point, I still think milk levels are subclinical.   TWH

 

Maternal iodine excess: an uncommon cause of acquired neonatal hypothyroidism.

Submitted by krewersf on 14 November 2018

All of us who work in pediatrics know that adequate thyroid function in a newborn is absolutely critical for the infants development.  Nothing is worse than hypothyroidism in a newborn infant.  While the infant needs low to modest levels of potassium iodine to make all the thyroxin it needs,  TOO MUCH iodine basically shuts the infant thyroid down.  Remember,  there is a pump in the human breast that collects all iodine molecules that pass the mothers breast and transfers that iodine molecule into the milk.  This was nature's way to make sure the baby could make

Deep breast pain during lactation: a case-control study in Sweden investigating the role of Candida albicans.

Submitted by krewersf on 14 November 2018

One of the most consistent rumors in human lactation for the last 30 years, has been that sore nipples are often caused by Candia Albicans infections.  Several of us have published that his etiology of sore nipples is completely wrong,  but this "syndrome" continues to be discussed in the beastfeeding field.  This study below, again,  clearly suggests that Candida as a cause of sore nipples,  is wrong.  Sorry folks,  its something else.   TWH

 

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